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Updated: Jul 17, 2026

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations
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A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations

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复杂的WT1相关疾病的遗传背景的审查

China Nagano1, Kandai Nozu2

  • 1Department of Pediatrics, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-Cho, Chuo-Ku, Kobe, 650-0017, Japan. china@med.kobe-u.ac.jp.

Clinical and experimental nephrology
|July 13, 2024
PubMed
概括

威尔姆斯瘤1 (WT1) 基因对脏发育和细胞维护至关重要. 与WT1相关的疾病,包括丹尼斯-德拉什综合征和弗雷泽综合征,显示出基于遗传突变的多种脏和瘤风险.

关键词:
在C2H2的基础上.结合 DNA 的 DNA 结合.丹尼斯 - 德拉什综合征弗雷泽综合症是什么?在WT1中,WT1就是WT1.

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