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Updated: Jun 21, 2025

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流体剪切压力介导的Piezo1通过激活PI3K/Akt通路来缓解骨细胞亡

Hongwei Zhan1, Daijun Xie2, Zhenxing Yan2

  • 1The Second Hospital of Lanzhou University, Orthopaedic Clinical Research Center of Gansu Province, Intelligent Orthopaedic Industry Technology Center of Gansu Province, Lanzhou, Gansu, China; Department of Joint Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, China.

Biochemical and biophysical research communications
|July 13, 2024
PubMed
概括

液体剪切应力 (FSS) 在骨细胞中调节Piezo1,通过PI3K/Akt通路保护脱甲诱导的亡. 降低Piezo1的调节会使亡恶化,突出显示它的保护作用.

关键词:
流体剪切应力是流体剪切应力.葡萄糖皮质类药物是什么骨质细胞是骨质细胞的组成部分.骨质疏松症是一种骨质疏松症.这是一个Piezo1.

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