在辅助剂中配制的BCG疫苗的增强疗效取决于IL-17A的表达

Steven C Derrick1, Amy Yang1, Siobhan Cowley1

  • 1Center for Biologics Evaluation and Research, United States Food and Drug Administration, Silver Spring, MD, USA.

概括

一种新的结核病 (TB) 疫苗辅助剂,DDA/TDB,通过增强IL-17A免疫反应来增强BCG疫苗的疗效. 在小鼠中这种改善的免疫控制表明了一种有希望的新策略来对抗结核病感染.

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