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Updated: Jun 21, 2025

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晶体结构和PPM1D氨酸/氨酸酸酶催化域的机制研究

Jay Prakash Kumar1, Dalibor Kosek2, Stewart R Durell1

  • 1Laboratory of Cell Biology, NCI, National Institutes of Health, Bethesda, Maryland, United States.

The Journal of biological chemistry
|July 13, 2024
PubMed
概括

我们确定了蛋白酸酶1D (PPM1D) 的第一个晶体结构,揭示了它的活性位点和独特的结构特征. 这个结构为PPM1D提供了洞察力.

关键词:
在B-loop中使用B-loop.2+) 离子中的.这是一个NOS桥梁.在PPM1D中,它是PPM1D.催化领域 催化领域晶体结构 晶体结构酶动力学 酶动力学这里是flap子域名.金属依赖的蛋白质酸酶.胺/三胺蛋白酸酶是一种蛋白酸酶.

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