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Updated: Jun 21, 2025

Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants
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在混合血统的白血病细胞中,MLL-AF9调节了转录的启动

Zimei Yang1, Ge Zhang2, Ruoyu Zhao1

  • 1Sheng Yushou Center of Cell Biology and Immunology, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.

The Journal of biological chemistry
|July 13, 2024
PubMed
概括

混合血统白血病融合蛋白 (MLL-FPs) 和AF9主要占据基因促进器,可能调节转录启动,而不仅仅是延长. 这挑战了人们对白血病中MLL-FP机制的现有理解.

关键词:
在AF9 AF9 AF9 AF9 AF9 AF9在MLL-AF9在MLL1中,MLL1是MLL1启动 启动 启动混合血统白血病的一种.超长延伸复合体是一个超长延伸复合体.

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