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高强度间歇训练可以改善多发性硬化症患者的骨重塑,脂质概况和身体功能

Alessandra Amato¹, Patrizia Proia², Anna Alioto³

¹Department of Biomedical and Biotechnological Sciences, Section of Anatomy, Histology and Movement Science, School of Medicine, University of Catania, Via S. Sofia No 97, 95123, Catania, Italy.

Scientific reports

|July 13, 2024

概括

高强度间歇训练 (HIIT) 在8周内显著改善了多发性硬化症 (MS) 患者的神经运动能力,骨形成和脂质谱. 这种运动干预为管理多发性硬化症症状和改善整体健康提供了一个有希望的方法.

科学领域:

神经学神经学
运动生理学运动生理学
代谢健康代谢健康

背景情况:

多发性硬化症 (MS) 是一种慢性自身免疫性,炎症性,脱髓性和神经退行性疾病,其病因不明.
身体活动被认为是提高神经病理状况患者生活质量的关键因素.

研究的目的:

研究高强度间歇训练 (HIIT) 对骨和脂质代谢标记物的潜在益处.
评估HIIT对多发性硬化症患者神经运动能力的影响.

主要方法:

16名患有多发性硬化症的参与者被随机分配到对照组 (不运动) 和运动组 (HIIT).
运动组每周3次进行8周的远程HIIT协议,由运动学家监督.
在基线 (T0) 和干预后 (T1) 测量了身体功能测试,骨重塑标记物和脂质配置文件.

主要成果:

观察到墙壁坐和Time Up and Go测试的表现有显著改善,这表明下肢力量和步态控制得到了增强.
脂质资料显示,总和LDL胆固醇水平显著降低.
骨代谢标志物表明骨质素 (骨形成) 的增加,并改善了25-OH维生素D水平.

结论:

八周的HIIT对MS患者的下肢力量和步态控制产生了积极的影响.
HIIT在改善骨形成标记物和管理脂质配置文件方面表现出好处.
这项研究表明,HIIT是改善多发性硬化症患者身体功能和代谢健康的可行干预措施.

关键词:

适应的体力活动.生物化学参数的参数骨标记物骨标记物骨标记物协调协调协调多发性硬化症是多发性硬化症.肌肉生理学肌肉生理学运动运动运动运动运动.培训培训培训培训培训

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