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Updated: Jun 21, 2025

Developing a Rat Model for Bipolar Disorder
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与双相情感障碍相关的误解变体改变了腺环酶2的活性,并促进了类似躁狂的行为

Paromita Sen1, Oskar Ortiz2, Elena Brivio3,4,5

  • 1Molecular Neurogenetics, Max Planck Institute of Psychiatry, 80804, Munich, Germany.

Molecular psychiatry
|July 13, 2024
PubMed
概括

与双相情感障碍 (BD) 相关的特定ADCY2基因突变损害了其功能,导致小鼠的躁狂症状和认知缺陷. 这项研究验证了ADCY2作为BD风险基因,并提出了新的治疗点.

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