分子证据表明,与精神分裂症中脑中神经炎症相关的应激反应发生变化

Sophie R Debs1, Debora A Rothmond2, Yunting Zhu3

  • 1Preclinical Neuropsychiatry Laboratory, Neuroscience Research Australia, Randwick, New South Wales, 2031, Australia; Discipline of Psychiatry & Mental Health, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, 2052, Australia.

概括

精神分裂症涉及中脑中变化的压力路径. 观察到葡萄糖皮质体受体 (GR) mRNA的减少和FKBP5 mRNA的增加,特别是在高度炎症的情况下,可能会使应激反应减弱.

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