与Leptochoroid和Pseudodrusen相关的维特利形病变
Serena Fragiotta1, Mariacristina Parravano2, Giulia Corradetti3
1Ophthalmology Unit, "Sapienza" University of Rome, NESMOS Department, St. Andrea Hospital, Rome, Italy.
Ophthalmology. Retina
|July 14, 2024
概括
勒普托维特利形黄斑病 (LVM) 是一种与视力威胁并发症的风险更高相关的独特疾病. 早期识别至关重要,因为它的进展速度更快,缩率增加.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜疾病 视网膜疾病
- 斑点退化症 斑点退化症
背景情况:
- 维特利形病变代表了一系列的黄斑疾病.
- 莱普托维特利型黄斑病 (LVM) 是一种特定的表型,其特征是下状状沉积物 (SDD) 和薄状状物 (leptochoroid).
- 了解LVM的临床和预后影响对于患者管理至关重要.
研究的目的:
- 描述 LVM 的临床和预后影响.
- 为了将LVM与其他形病变表型进行比较,包括获得的形病变 (AVL) 和单独的SDD.
主要方法:
- 60只眼睛 (20 LVM,20 AVL,20 SDD) 的回顾性队列研究.
- 纳入标准:年龄>50,完整的记录,多式成像和≥6个月的随访.
- 结果措施包括冠状腺血管性指数 (CVI) 和晚期并发症 (新血管化,缩).
主要成果:
- 与AVL (20%) 和SDD (20%) 组相比,LVM眼睛的晚期并发症比例较高 (55%).
- 卡普兰-梅尔分析显示,LVM患者的缩发展显著加快 (中位数为3.9年) 与对照组 (7.1年) 相比.
- LVM的存在与发展并发症的可能性增加了四倍.
结论:
- 莱普托维特利状黄斑病是维特利状病变谱中一个独特的临床实体.
- LVM与快速进展和并发症的更高倾向有关,特别是缩转化.
- 对于预测视觉结果而言,LVM的临床差异化很重要.
相关概念视频
01:25Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
01:30Bacterial Phylum Spirochaetes
Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased by a...