在鼻炎和慢性鼻炎中,患者报告的结果指标
Mark S Dykewicz1, Dana V Wallace2, Sindhura Bandi3
1Section of Allergy and Immunology, Department of Internal Medicine, Saint Louis University School of Medicine, Saint Louis, Mo.
概括
患者报告的结果测量 (PROM) 对于评估鼻炎和慢性鼻炎 (CRS) 是至关重要的. 虽然有价值,但在选择,管理和解释PROM方面仍然存在挑战,以实现最佳的临床决策和患者护理.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 临床结果研究研究
- 医疗保健服务研究 医疗服务研究
背景情况:
- 患者报告的结果测量 (PROM) 是评估鼻炎和慢性鼻炎 (CRS) 的重要工具.
- PROM捕捉患者的体验,包括症状,疾病控制,幸福感和生活质量 (QOL).
- 这些措施经常在临床试验和实践中使用,比如在药物治疗或免疫治疗等干预措施之前和之后.
研究的目的:
- 审查PROMs在炎和CRS管理中的当前情况和挑战.
- 要突出不同PROM类型 (症状,疾病控制,QOL) 的不同验证水平.
- 讨论CRS中疾病控制测量的不断发展的概念.
主要方法:
- 文献综述和现有关于PROMs治疗鼻炎和CRS的现有研究的综合.
- 分析特定PROM的验证状态和常用情况.
- 确定PROMs临床应用中的挑战.
主要成果:
- 鼻炎生活质量问卷是对过敏性鼻炎 (AR) 最有效的PROM.
- 对于AR和CRS的症状和疾病控制PROM,没有普遍接受的标准标准.
- 22项的鼻结局测试是CRS常用的QOL测量标准.
- 许多标准 (至少15个) 已被用于对抗CRS疾病,这表明定义在不断变化.
结论:
- PROMs至关重要,但在临床实施中面临挑战,包括仪器选择,施用协议和患者/提供者的负担.
- 对鼻炎和CRS的症状和疾病控制PROMs需要进一步标准化和验证.
- 应对并发症和问卷疲劳等挑战对于在共享决策中有效利用PROM至关重要.
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