在中风和痴呆症发展中转移行为与环境风险相关
Kung-Min Wang1, Shih-Hsien Tseng1, Chia-Min Lee1
1Department of Industrial Management, National Taiwan University of Science and Technology, Taipei, Taiwan.
Geriatrics & gerontology international
|July 15, 2024
概括
慢性疾病和环境因素对中风和痴呆症的过渡有重大影响. 主要影响因素包括性别,年龄,失业和空气污染,这突出了65岁以下男性的风险.
科学领域:
- 医疗信息学 医疗信息学
- 环境信息学环境信息学
- 公共卫生 公共卫生
背景情况:
- 慢性疾病是导致中风,痴呆和死亡的主要原因.
- 环境风险越来越多地被认为是中风到痴呆症过渡的因素.
- 了解这些转变对于公共卫生干预至关重要.
研究的目的:
- 研究从慢性疾病到中风,从中风到痴呆的过渡行为.
- 评估慢性疾病和环境风险因素对这些转变的影响.
- 为了确定中风和随后的痴呆症的高风险亚群.
主要方法:
- 一个综合调查的医疗和环境信息学数据从10627个中风患者在台湾.
- 应用共变量模型和子组分析.
- 评估慢性疾病和环境因素 (离婚,失业,孤独,温度,空气污染).
主要成果:
- 构建了98个共变量模型,分析了14种过渡类型.
- 在98个转变中,有26个转变具有统计学意义.
- 性别,年龄,离婚率,失业率,温度和空气污染影响了慢性疾病到中风的过渡.
- 性别,年龄,失业率和温度影响了中风到痴呆症的过渡.
结论:
- 环境因素和人口变量显著影响疾病进展途径.
- 65岁及以下的男性代表了中风和痴呆的高风险群体.
- 研究结果强调需要针对性干预,同时考虑临床和环境因素.
相关概念视频
Dementia
110
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
The progression of dementia is generally gradual....
110
Parkinson's Disease: Overview
522
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
522
Cognitive Development During Adulthood
83
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
83
Alzheimer's Disease: Treatment
177
Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
177


