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Updated: Jun 21, 2025

Measurement of Heme Synthesis Levels in Mammalian Cells
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Measurement of Heme Synthesis Levels in Mammalian Cells

Published on: July 9, 2015

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一个适配器,通过线粒体蛋白酶CLPXP反调节血红素生物合成

Thomas Cottle, Lydia Joh, Cori Posner

    bioRxiv : the preprint server for biology
    |July 15, 2024
    PubMed
    概括

    POLDIP2充当血红蛋白传感器,提供血红蛋白生物合成酶ALAS,由CLPXP蛋白酶复合体降解. 这一发现澄清了血红素反调节和病机制.

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