在自然食和饮酒期间,在口面感觉运动皮质中进行3D定向调整
Victoria B Hosack1, Fritzie I Arce-McShane1,2,3
1Department of Oral Health Sciences, School of Dentistry, University of Washington, Seattle, WA.
bioRxiv : the preprint server for biology
|July 15, 2024
概括
研究人员研究了大脑如何编码饮食和饮酒期间的3D舌头运动. 他们发现,口腔面部感觉运动皮质 (OSMCx) 显示了定向调整,这受口腔感觉丧失的影响.
科学领域:
- 神经科学是一个神经科学.
- 发动机控制器的控制器
- 感官运动一体化 感官运动一体化
背景情况:
- 舌头的方向运动对于食,说话和吞至关重要.
- 了解3D舌头运动编码在耳面皮质中的编码对于治疗口舌功能障碍至关重要.
研究的目的:
- 在自然行为过程中调查口腔面感运动皮质 (OSMCx) 中的3D舌头运动编码.
- 为了确定口腔感官损失如何影响这种神经编码.
主要方法:
- 双平面视频放射学追踪了非人类灵长类动物 (Macaca mulatta) 的3D舌头运动.
- 从主要运动 (MIo) 和体感 (SIo) 或面皮层同时进行的神经记录.
- 使用三角神经块暂时阻断了口腔感觉.
主要成果:
- 大多数MIo神经元,但不是SIo神经元,在食期间显示了3D定向调.
- 在MIo和SIo中,大多数神经元都在饮酒时调整为舌头突起方向.
- 感觉损失减少了方向调节的神经元的比例,并在OSMCx中转移了首选方向.
结论:
- MIo和SIo神经元的3D定向调整因行为任务 (食与饮酒) 而有所不同.
- 感官信息显著影响OSMCx中舌头运动的神经表现.
- 研究结果提供了关于口语控制和口语功能障碍康复的神经机制的见解.
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