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Updated: Jun 21, 2025

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
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原蛋白修饰重塑了肉瘤瘤的微环境,并促进了对免疫检查点抑制的抵抗力

Hehai Pan, Ying Liu, Ashley M Fuller

    bioRxiv : the preprint server for biology
    |July 15, 2024
    PubMed
    概括

    普洛-氨酸,2-氧格酸-5-二氧化酶2 (Plod2) 在软组织肉瘤中促进免疫逃避. 用米诺克西迪尔抑制Plod2可减少瘤生长,并增强无差异多形肉瘤中抗PD-1免疫疗法的疗效.

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