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Updated: Jun 21, 2025

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螺旋介导的TDP-43 C终端域多元化的结构细节

Azamat Rizuan1, Jayakrishna Shenoy2, Priyesh Mohanty1

  • 1Artie McFerrin Department of Chemical Engineering, Texas A&M University, College Station, TX 77843.

bioRxiv : the preprint server for biology
|July 15, 2024
PubMed
概括

研究人员发现了TAR DNA结合蛋白-43 (TDP-43) 保护区域的螺旋结构,这对其功能至关重要,并且与像ALS这样的神经退行性疾病有关. 这一发现澄清了TDP-43的情况.

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