Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Statistical Software for Data Analysis and Clinical Trials01:12

Statistical Software for Data Analysis and Clinical Trials

532
Statistical software is pivotal in data analysis and clinical trials by providing tools to analyze data, draw conclusions, and make predictions. These software packages range from simple data management applications to complex analytical platforms, supporting various statistical tests, models, and simulation techniques. Their significance lies in their ability to handle vast amounts of data with precision and efficiency, enabling researchers to validate hypotheses, identify trends, and make...
532
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

5.7K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
5.7K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Acceptability of Nonpharmaceutical Interventions to Prevent the Risk of COVID-19 Infection in the United States.

MDM policy & practice·2026
Same author

Geographic diversity in top dermatology journal editorial boards.

The British journal of dermatology·2026
Same author

Diagnosis and management of acyclovir-resistant herpes simplex virus for the dermatologist.

Journal of the American Academy of Dermatology·2026
Same author

Correlated gene copy number changes in a seminal fluid protein network in <i>Drosophila</i>.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

The Stellate meiotic drive system of Drosophila melanogaster is active in contemporary populations.

Genetics·2026
Same author

Comparative impacts and cost-effectiveness of tuberculosis systematic screening strategies in prisons in Brazil, Colombia, and Peru: A mathematical modeling study.

PLoS medicine·2026
Same journal

Layered social competition coordinates reproductive hierarchy formation in ants.

bioRxiv : the preprint server for biology·2026
Same journal

Combination epigenetic-targeted therapy increases the immunogenicity of poorly immunogenic sarcomas.

bioRxiv : the preprint server for biology·2026
Same journal

Loss of LanC-like proteins delays post-injury regeneration of aging skeletal muscles.

bioRxiv : the preprint server for biology·2026
Same journal

Integrative Transfer Network: Deep Transfer Learning Across Populations and Prediction Targets.

bioRxiv : the preprint server for biology·2026
Same journal

Confidence-supported label-free metabolic imaging with FPhaS phase autofluorescence microscopy.

bioRxiv : the preprint server for biology·2026
Same journal

Sequence-encoded autoinhibition couples mRNA decapping activity to phase separation.

bioRxiv : the preprint server for biology·2026
查看所有相关文章

相关实验视频

Updated: Jun 21, 2025

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

2.1K

e3SIM:基因组流行病学的流行病学-生态-进化模拟框架.

Peiyu Xu1, Shenni Liang2, Andrew Hahn2

  • 1Department of Molecular Biology & Genetics, Cornell University, Ithaca, NY, USA.

bioRxiv : the preprint server for biology
|July 15, 2024
PubMed
概括
此摘要是机器生成的。

一个新的模拟器,e3SIM,将传染病传播,病原体进化和环境因素一起进行模拟. 该工具增强了对疾病动态的理解,以改善公共卫生战略.

更多相关视频

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.
22:27

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.

Published on: May 6, 2010

408.9K
Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA
11:35

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA

Published on: August 21, 2016

13.0K

相关实验视频

Last Updated: Jun 21, 2025

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

2.1K
Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.
22:27

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.

Published on: May 6, 2010

408.9K
Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA
11:35

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA

Published on: August 21, 2016

13.0K

科学领域:

  • 流行病学 流行病学
  • 生态生态学 生态生态学
  • 进化生物学 进化生物学
  • 计算生物学 计算生物学

背景情况:

  • 传染病的动态涉及流行病学,生态学和进化因素之间的复杂相互作用.
  • 当前的模型往往过于简化了这些相互作用,无法捕捉病原体进化如何影响传播.
  • 准确的建模对于了解疾病传播和为公共卫生干预提供信息至关重要.

研究的目的:

  • 引入流行病学-生态-进化模拟器 (e3SIM),这是一个开源的综合建模框架.
  • 提供一种同时模拟病原体传播,分子进化和环境影响的工具.
  • 为研究复杂的传染病系统提供灵活和可扩展的平台.

主要方法:

  • 开发了一个基于代理的,离散生成的,时间前进的模拟器 (e3SIM).
  • 综合区间模型,宿主接触网络和定量特征病原体模型.
  • 集成的时间变化的环境因素和图形用户界面.

主要成果:

  • e3SIM可以同时建模疾病传播和病原体分子演变.
  • 该框架是模块化,可扩展和灵活的,用于各种流行病学和遗传学复杂性.
  • 通过真实的SARS-CoV-2和Mycobacterium结核病爆发模拟来证明其能力.

结论:

  • e3SIM提供了一种全面的方法来建模传染病动态.
  • 该模拟器有助于研究各种病原体类型的基因组流行病学.
  • 为推进公共卫生研究和战略制定提供了有价值的工具.