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Updated: Jun 21, 2025

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
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生物催化,对三级C-H债券的富含酵素的初级氨基化

Runze Mao1, Shilong Gao1, Zi-Yang Qin1

  • 1Division of Chemistry and Chemical Engineering, California Institute of Technology Pasadena, California 91125, United States.

Nature catalysis
|July 15, 2024
PubMed
概括

一种工程酶,P411-TEA-5274,可以实现三级C-H键的直接不对称氨基化. 这一突破创造了具有高效率和酶选择性的奇拉性α-三级原胺.

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