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Updated: Jun 21, 2025

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顶向下的蛋白质组学

David S Roberts1,2, Joseph A Loo3, Yury O Tsybin4

  • 1Department of Chemistry, Stanford University, Stanford, CA, USA.

Nature reviews. Methods primers
|July 15, 2024
PubMed
概括

顶向下蛋白质组学 (TDP) 分析整个蛋白质,以了解它们在疾病中的功能和作用. 这种方法提供了对蛋白质组的整体观点,推进了精准医学和生物系统的理解.

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Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
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