哺乳过早的婴儿会影响母乳中的微生物组成
Lijuan Long1, Hongjuan Bi1,2, Shangjuan Zeng1
1Department of Neonatology, Guangxi Zhuang Autonomous Region Maternal and Child Health Hospital Nanning, Guangxi Zhuang Autonomous Region, China.
American journal of translational research
|July 15, 2024
概括
哺乳早产婴儿显著改变人乳细菌群落. 特定的细菌如Bacillus和Lactobacillales在养前后都表现出丰富,影响婴儿的发育.
科学领域:
- 微生物学 微生物学
- 新生儿科学 新生儿科学
- 人类牛奶研究研究
背景情况:
- 过早出生的婴儿往往具有改变的肠道微生物群.
- 母乳是婴儿营养和免疫因素的重要来源.
- 哺乳对早产婴儿母乳细菌成分的影响尚未完全理解.
研究的目的:
- 研究母乳养如何影响早产婴儿母乳中的细菌群落.
- 为了比较母乳养前后的细菌组成,与婴儿早产和出生体重相关.
主要方法:
- 从40名早产婴儿的母亲那里收集了母乳样本,这些婴儿在母乳养之前和之后.
- 婴儿被分为极早产 (EPM),极早产 (VPM),极低出生体重 (VLBW) 和极低出生体重 (ELBW) 组.
- 使用高通量测序分析了细菌组成.
主要成果:
- 哺乳显著改变了HM细菌的多样性.
- 在养之前,Bacillus,Prevotella和Fusobacterium都进行了丰富.
- 乳球菌,菌和Elizabethkingia meningoseptica在养后得到了丰富,特别是在EPM组.
- 在VLBW婴儿中观察到菌丰富在养前和乳酸菌在养后.
- HM细菌多样性与婴儿发育和免疫结果有中等的相关性.
结论:
- 哺乳对于早产婴儿来说,在塑造母乳中的细菌成分方面发挥着重要作用.
- 这些HM细菌的变化可能对早产婴儿的发育和免疫有影响.
相关概念视频
01:23Anatomy of the Intestines
71.7K
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
71.7K
01:18Surface Membrane Barriers
1.1K
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
1.1K
01:29Bacterial Flora of the Large Intestine
416
The gut microbiome is formed by a vast and diverse community of bacteria that colonizes our large intestine. These bacteria start residing in the gut from birth and continue diversifying throughout life, influenced by factors such as diet, lifestyle, and stress. The gut bacterial community also includes bacteria from food and those that enter the colon through the anus.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
416
01:26Factors Affecting the Risk of Infection
11.6K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.6K