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基于ARTIC-/Illumina的全基因组测序协议和SARS-CoV-2分析管道的优化数据

Christian Bundschuh1, Niklas Weidner1,2, Julian Klein1

  • 1Medical Faculty Heidelberg, Department of Infectious Diseases Virology, Heidelberg University, Heidelberg, Germany.

Data in brief
|July 15, 2024
PubMed
概括

德国从2021年至2023年监测了SARS-CoV-2变种,以控制大流行. 全基因组测序发现了关键突变,有助于公共卫生工作.

关键词:
生物信息学是一种生物信息学.流行病学 流行病学这就是SARS-CoV-2病毒.病毒学 病毒学整个基因组的测序.

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Sanger Sequencing01:57

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DNA sequencing is a fundamental technique that is routinely used in the biological sciences. This method can be applied to a range of questions at different scales - from the sequencing of a cloned DNA fragment or the study of a mutation in a gene up to whole-genome sequencing. However, despite the widespread use of sequencing today, it was not until 1977 that Fredrick Sanger and his collaborators developed the chain-termination method to decode DNA sequences. It relies on the separation of a...