在百万退伍军人计划参与者中,增加的BMI与减少的母乳养开始有关
medRxiv : the preprint server for health sciences
|July 15, 2024
概括
更高的产前体重指数 (BMI) 与开始母乳养的可能性较低有关. 体重指数较高的女性可能会从产后母乳养支持中受益,以获得成功的婴儿营养.
科学领域:
- 生殖健康 生殖健康
- 公共卫生 公共卫生
- 遗传学 是一个遗传学.
背景情况:
- 哺乳提供了母婴健康的好处.
- 产前体重指数 (BMI) 与母乳养时间相反相关.
- 哺乳和BMI都受社会经济因素的影响.
研究的目的:
- 调查产前体重指数 (BMI) 与母乳养开始之间的关联.
- 探索遗传倾向对BMI在母乳养可能性中的作用.
主要方法:
- 利用了来自百万退伍军人计划的女性参与者的数据.
- 提取的BMI和BMI计算的多基因分数 (PGS).
- 采用孟德尔的随机化来评估基因预测的BMI和母乳养之间的因果关系.
主要成果:
- 产前BMI增加显著预测了母乳养一个月或更长时间的可能性较低.
- 产前BMI增加5kg/m2与母乳养几率下降24%有关.
- 基因预测的BMI增加5kg/m2与母乳养的几率降低17%有关.
结论:
- 体重指数 (BMI) 升高是母乳养时间缩短的预测指标.
- 体重指数较高的女性可能需要加强产后母乳养支持.
- 促进母乳养的干预措施应将BMI视为影响成功的因素.
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