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Updated: Jun 21, 2025

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Quantification of Hypopigmentation Activity In Vitro
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帕尔博西克利布诱导的 Vitiligo-Like 病变:一个具有挑战性的病例报告
Abdulmohsin K Algethami1, Alhusain M Alshareef1, Waseem K Alhawsawi2
1Dermatology, King Abdulaziz Medical City, Jeddah, SAU.
Cureus
|July 15, 2024
概括
帕尔博西克利布 (Palbociclib) 是一种用于晚期乳腺癌的CDK4/6抑制剂,可导致罕见的白风样皮肤脱色. 这一案例凸显了对管理这种副作用的认识和进一步研究的需要.
科学领域:
- 在瘤学瘤学.
- 皮肤病学 皮肤病学
- 药理学 药理学是指药理学的学科.
背景情况:
- 环素依赖激酶 (CDK) 4和6抑制剂,包括palbociclib,是激素受体阳性 (HR+),人体表皮生长因子受体2-阴性 (HER2-) 先进或转移性乳腺癌的标准治疗方法.
- 虽然有效,但这些向疗法与潜在的皮肤学不良事件有关,例如白风样色素丧失.
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