在非膜性心房动患者的左心房尾闭塞后心脏功能和结构的比较,而不是对非膜性心房动患者的剥离:一项回顾性研究
Zhong-Bao Ruan1, Fei Wang1, Ge-Cai Chen1
1Department of Cardiology, the affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou 225300, P.R. China.
International journal of medical sciences
|July 15, 2024
概括
在非膜性心房动 (NVAF) 患者的左心房尾闭塞 (LAAO) 显著降低了NT-proBNP水平. 然而,单独使用LAAO不会显著影响心脏结构或功能;改善归因于结合式废除疗法.
科学领域:
- 心脏病学 心脏病学
- 医疗器械 医疗器械
- 电子生理学 电子生理学
背景情况:
- 非膜性心房动 (NVAF) 存在中风和心力衰竭的风险.
- 左心房尾阻塞 (LAAO) 是抗凝药的替代方案,用于预防NVAF中风.
- 对LAAO对心脏功能和结构的长期影响需要进一步研究.
研究的目的:
- 评估LAAO对NVAF患者心脏功能和结构的长期影响.
- 为了比较简单的LAAO与LAAO与消去结合的结果.
主要方法:
- 一项涉及157名接受LAAO或联合治疗的NVAF患者的研究.
- 患者被分为简单的LAAO和结合的LAAO与切除组.
- 长期评估心脏结构 (LAAD,LVEDD,LVESD) 和功能 (LVEF),以及NT-proBNP水平.
主要成果:
- LAAO手术成功,并发症率为6.4%.
- 单独LAAO对心脏结构或功能没有显著变化,但在6个月和12个月后减少了NT-proBNP.
- 结合疗法在LAAD,LVEDD,LVESD,NT-proBNP和LVEF中显示出显著的改善.
结论:
- 单独使用LAAO不会显著改变NVAF患者的心脏结构或功能.
- 实际上,LAAO有效地降低了NT-proBNP水平.
- 随着联合治疗观察到心脏结构和功能的改善主要是由于切除,而不是LAAO本身.
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