患有ipsilateral感染关节塑形患者周围假肢关节感染的风险
Robert M Wetzel1, Giovanni A Ayala2, Christopher W Grayson1
1Florida Orthopaedic Institute, Adult Reconstruction Service, Temple Terrace, FL, USA.
Arthroplasty today
|July 15, 2024
概括
在同一条腿上发展第二次周围假肢关节感染 (PJI) 的风险与另一条腿相似. 免疫抑制剂的使用可能会增加双侧PJI的风险.
科学领域:
- 整形外科手术 整形外科手术
- 传染性疾病 传染性疾病
- 生物医学工程 生物医学工程
背景情况:
- 在最初的PJI后,发展第二次周围假肢关节感染 (PJI) 的风险约为18%-20%.
- 有限的研究存在于二次PJI在ipsilateral关节的发生率.
- 本研究重新评估了ipsilateral PJI的发病率和风险因素.
研究的目的:
- 为了确定在最初的PJI之后,在ipsilateral关节中开发第二个PJI的发生率.
- 为了确定与ipsilateral PJI相关的潜在风险因素.
- 为了比较ipsilateral PJI与contralateral PJI的风险.
主要方法:
- 从2015年至2021年对下端PJI病例的回顾性审查.
- 包括多次ipsilateral关节置换的患者.
- 识别感染时间,风险因素,细菌来源和细菌性血症.
主要成果:
- 在392名PJI患者中,179人有多个假肢关节;47人有双侧假肢.
- 三名患者 (6.4%) 发展出双侧PJI;10名患者 (21.3%) 发展出单独的整体PJI.
- 免疫抑制剂的使用与发展第二个ipsilateralPJI (P = .02) 的可能性更高有关.
结论:
- 对于ipsilateral PJI的风险并不大于对应的PJI.
- 在一只四肢中感染TJA并不会显著增加对侧肢感染的风险.
- 免疫抑制剂的使用可能是发展单独的ipsilateral PJI的危险因素.
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