男性乳腺癌的生存模式:与女性乳腺癌不同
Sungchan Gwark1, Jisun Kim2, Il Yong Chung2
1Department of Surgery, Ewha Womans University College of Medicine, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea.
Frontiers in oncology
|July 15, 2024
概括
男性乳腺癌 (MBC) 的生存模式与女性乳腺癌有很大的不同. 年轻的MBC患者表现出更好的生存率,与女性不同,突出了独特的疾病特征.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
背景情况:
- 男性乳腺癌 (MBC) 是罕见的,与女性乳腺癌相比,它具有不同的特征.
- 了解MBC的长期生存结果和疾病模式对于改善患者预后至关重要.
研究的目的:
- 评估和对比男性乳腺癌患者与女性乳腺癌患者的长期生存结果和疾病模式.
- 为了确定男性乳腺癌的独特预后因素.
主要方法:
- 在1990年至2014年期间,韩国乳腺癌登记处 (KBCR) 分析了113,845名乳腺癌患者的大量队列.
- 男性和女性乳腺癌患者之间的临床病理学特征和五年总生存率的比较.
- 根据诊断时的年龄对男性和女性队列的生存分析的分层.
主要成果:
- 在113,845名患者中,473人被诊断出患有男性乳腺癌 (MBC).
- 在诊断时,MBC患者的年龄较大 (中位数为60岁),与女性患者 (中位数为48岁) 相比.
- 生存分析揭示了不同的模式:年轻的MBC患者 (≤40岁) 的5年总生存率 (97.4%) 比较老的MBC患者 (>40岁) (86.4%) 更好,与女性乳腺癌相比,年轻的患者的生存率更差.
结论:
- 男性乳腺癌表现出独特的长期生存模式,与女性乳腺癌观察到的不同.
- 诊断时的年龄是一个关键因素,在男性和女性乳腺癌中具有差异性预后影响.
- 这项研究增强了对MBC预后的理解,并为未来的研究方向提供了信息.
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