在前部纤维肌层受保护核化后,与年龄相关的丸激素升高的损伤
Ruei-Je Chang1, Chih-Yiu Tsai2,3, Han-Yu Tsai1,3
1Department of Urology, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.
概括
前列腺前纤维肌层保护核化 (AFSPE) 显著增加了男性良性前列腺阻塞 (BPO) 的血清丸激素水平. 年轻的患者经历了更大的升,这表明AFSPE改善了荷尔蒙健康以及尿路症状.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 内分泌学 在内分泌学.
- 手术创新 在外科创新.
背景情况:
- 良性前列腺阻塞 (BPO) 影响了大量老年男性.
- 低血清丸激素在BPO男性中很常见,可能会影响生活质量.
- 目前的BPO治疗可能无法解决潜在的荷尔蒙失衡.
研究的目的:
- 评估前纤维肌层保护性核化 (AFSPE) 对 BPO 患者血清丸激素水平的影响.
- 为了探索AFSPE后手术后丸激素变化的与年龄相关的差异.
- 评估丸激素变化与症状改善之间的相关性.
主要方法:
- 在2018年至2021年期间接受AFSPE治疗的304名患者的回顾性分析.
- 将患者分为低 (<3.5 ng/mL) 和正常 (≥3.5 ng/mL) 的手术前丸激素组.
- 在手术前和手术后1.5个月和3-6个月测量血清丸激素;对人口因素的分析.
主要成果:
- 在低丸激素组观察到显著的丸激素增加 (2.61到3.59 ng/mL在3-6个月内,p<0.0001).
- 正常丸激素组显示显著增加3-6个月 (至6.06 ng/mL,p=0.0079).
- 年龄较大与术后丸激素升高相反相关;在两组中都改善了夜.
结论:
- 在患有BPO的男性中,AFSPE有效地提高了血清丸激素,特别是那些初始水平较低的男性.
- 年龄是一个关键因素,年轻的患者可能会体验到更大的荷尔蒙益处.
- AFSPE具有双重益处,改善了荷尔蒙健康和下泌尿道症状.
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