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阻塞性睡眠呼吸暂停和关节疾病之间的关联:一个元分析

Cláudia Aparecida de Oliveira Machado¹, Camila Maria Bastos Machado de Resende², Juliana Stuginski-Barbosa³

¹Federal University of Uberlandia, Uberlândia, MG, Brazil.

Journal of oral rehabilitation

|July 15, 2024

概括

患有关节障碍 (TMD) 的患者也有明显更高的阻塞性睡眠呼吸暂停 (OSA) 的可能性. 建议所有TMD患者进行OSA查,以改善诊断和护理.

科学领域:

医学研究医学研究
睡眠医学睡眠医学
牙科医学牙科医学

背景情况:

阻塞性睡眠呼吸暂停 (OSA) 在患有关节疾病 (TMD) 的个体中很普遍.
目前,有限的证据支持OSA和TMD之间的直接联系.

研究的目的:

在成年人中系统地审查和元分析OSA和TMD之间的关联.
巩固现有的证据,证明这些条件的同时发生.

主要方法:

在多个数据库 (EMBASE,PubMed,Scopus等) 进行了搜索. 进行相关研究.
包括使用RDC/TMD或DC/TMD和OSA通过多睡眠学 (PSG) 和/或验证问卷评估TMD的研究.
对提取的数据进行了元分析,计算了几率比率 (OR) 和95%置信区间 (CI).
使用乔安娜·布里格斯研究所的检查清单评估了偏见风险,并使用GRADE对证据的确定性.

主要成果:

七项研究符合定性综合的纳入标准,六项研究符合定量分析的纳入标准.
在TMD和OSA之间发现了显著的积极关联 (OR = 2.61;95% CI = 2.312.95).
这种关联无论使用的OSA诊断方法 (PSG和/或问卷) 是否仍然显著.

结论:

TMD患者与OSA有显著的关联.
对于被诊断患有TMD的个人,建议进行常规的OSA查.
需要进一步研究更大的样本大小和标准化PSG,以完全澄清OSA-TMD关系.

关键词:

这是一个元分析.阻塞性睡眠呼吸暂停症是什么睡眠障碍睡眠障碍睡眠障碍系统性审查系统性审查关节关节疾病关节关节疾病

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