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与年龄相关的IGFBP2增加增加黑色素瘤细胞入侵和脂质合成

Gretchen M Alicea1,2, Payal Patel2, Marie E Portuallo1

  • 1Department of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.

Cancer research communications
|July 15, 2024
PubMed
概括

老化的皮肤细胞分泌更多的IGF结合蛋白2 (IGFBP2),这促进了黑色素瘤细胞的生长和扩散. 向IGFBP2可以减少黑色素瘤瘤的生长和老年人的转移.

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