对MRI研究对母亲肥胖对后代大脑结构和功能影响的系统审查
Mohammadamin Parsaei1, Seyedeh Melika Hashemi2, Hossein Sanjari Moghaddam3
1Maternal, Fetal & Neonatal Research Center, Family Health Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Journal of neuroscience research
|July 15, 2024
概括
孕产妇的肥胖会影响后代的大脑发育,影响其结构和功能,特别是在情绪和行为中心. 这篇综述强调了与孕产妇肥胖有关的大脑发育中的显著变化.
科学领域:
- 神经科学是一个神经科学.
- 发展生物学 发展生物学
- 公共卫生 公共卫生
背景情况:
- 怀孕前和怀孕期间的孕产妇肥胖与后代的不良神经发育和心理健康结果有关.
- 这些结果中介的特定的大脑结构和功能变化仍然不清楚.
研究的目的:
- 系统地审查磁共振成像 (MRI) 研究,检查母亲肥胖和后代大脑测量之间的关联.
- 综合有关母亲肥胖如何影响胎儿和儿童大脑发育的研究结果.
主要方法:
- 在PubMed,科学网,Scopus和PsycINFO的系统文献搜索到2023年8月20日.
- 包括使用功能性MRI (fMRI),扩散张力成像 (DTI) 和解剖MRI的15项研究.
- 分析跨不同后代年龄组的研究,从胎儿到成年人.
主要成果:
- 15项研究中有12项报告说,母亲肥胖和后代大脑变化之间存在显著的关联.
- 最常见的变化是在前额叶皮和边缘系统中观察到的.
- 研究结果表明,它对大脑结构和功能都有影响.
结论:
- 孕产妇的肥胖对后代的大脑发育产生重大影响,特别是影响前额叶和边缘网络,这对情绪和行为调节至关重要.
- 需要进一步的研究来阐明这些大脑变化的调解机制和长期后果.
- 研究这些影响背后的分子通路是必不可少的.
相关概念视频
Magnetic Resonance Imaging
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
Imaging Studies for Cardiovascular System IV: CMRI
Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
Imaging Studies IV: Magnetic Resonance Imaging
Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...


