总体上胃肠道癌的发病率死亡率的种族,种族和性别差异
Alyyah Malick1, Jennifer S Ferris2, Chin Hur3
1Division of Digestive and Liver Diseases, Department of Medicine, Columbia University Irving Medical Center, New York, New York, USA.
Clinical and translational gastroenterology
|July 15, 2024
概括
上部胃肠道 (UGI) 癌症不成比例地影响少数民族男性,突出显示出严重的基于种族的死亡率差异. 目前的查策略忽视了这些脆弱人群,需要重新评估UGI癌症早期检测.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 目前的上部胃肠道 (UGI) 癌症查侧重于食道腺癌 (EAC) 风险.
- 所有UGI癌症都可以通过上部内镜检测到.
- 本研究调查了累积UGI癌症的基于发病率的死亡率 (IBM),以确定差异.
研究的目的:
- 评估和探索累积上部胃肠道 (UGI) 癌症的基于发病率的死亡率 (IBM).
- 为了确定UGI癌症死亡率的基于种族和基于性别的差异.
- 为了比较UGI癌症IBM与结直肠癌IBM.
主要方法:
- 使用了监测,流行病学和最终结果 (SEER) 数据 (2000-2019).
- 分析了被诊断患有EAC,食道状细胞癌,心脏胃癌,非心脏胃癌或结肠直肠腺癌的患者.
- 根据年龄调整计算的IBM,按性别和种族/种族分层.
主要成果:
- 累积的UGI癌症IBM是每10万人的8.40.
- 最高的癌症特异性IBM率是EAC,其次是非心脏胃癌.
- 黑人男性 (16.43),美国印第安人/阿拉斯加土著男性 (15.23) 和西班牙裔男性 (13.76) 中的UGI癌症IBM最高.
结论:
- 在非白人人口亚群中,UGI癌症对非白人人口亚群的死亡率负担明显更高.
- 这些差异表明目前的查方法不足.
- 在服务不足的UGI癌症人群中,有必要进行系统查.
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