早期营养对与早产儿处理速度相关的大脑区域的影响:随机试验的二次分析
Nicole Bando1,2, Julie Sato3,4,5, Marlee M Vandewouw4,5,6,7
1Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada.
JPEN. Journal of parenteral and enteral nutrition
|July 15, 2024
概括
早期营养影响早产婴儿的发育. 母乳,而不是宏观营养素,与较大的灰质体积有关,支持出生体重非常低的儿童的处理速度.
科学领域:
- 神经科学是一个神经科学.
- 发育儿科 发育儿科
- 营养科学 营养科学
背景情况:
- 处理速度对于情报和执行功能至关重要.
- 过早出生的孩子通常会在这些认知领域出现延迟.
- 早期营养在支持早产婴儿处理速度发展中的作用尚不清楚.
研究的目的:
- 调查早期营养与大脑灰质体积之间的关联,支持早产儿的处理速度.
- 为了确定宏观营养素摄入量或母乳消费是否会影响加工速度的结构基础.
主要方法:
- 磁共振成像 (MRI) 用于评估大脑灰质量在40个五岁的孩子出生早产,出生时体重非常低.
- 进行了Wechsler幼儿园和小学智力尺度-IV处理速度指数的管理.
- 早期营养摄入量 (宏观营养素和母乳) 在出生后的第一个月前性地收集.
主要成果:
- 母乳摄入量与关键大脑区域的灰质量增加有关,包括皮质灰质总量,环状回转和状回转.
- 早期的宏观营养素摄入量与灰质体积没有显著的关联.
- 妊娠年龄平均为27.8周,其中45%的参与者是男性.
结论:
- 产后早期母亲的牛奶摄入量与早产儿的处理速度相关的灰质体积有关.
- 第一个月的宏观营养素摄入量没有显示出类似的关联.
- 这些发现表明,母乳可能支持早产婴儿处理速度的结构发展,这需要进一步研究.
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