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在口腔健康研究中报告观察性研究和临床试验的OHStat指南:手稿检查清单
A M Best1, T A Lang2, B L Greenberg3
1School of Dentistry and Department of Biostatistics, School of Medicine, Virginia Commonwealth University, Richmond, Virgina.
Journal of endodontics
|July 15, 2024
概括
新的OHStat指南改善了口腔健康研究报告. 这些指导方针提高了牙科观察性研究和临床试验的透明度和评估.
科学领域:
- 口腔健康研究研究 口腔健康研究
- 生物统计学 生物统计学
- 临床试验 临床试验
- 观察性研究 观察性研究
背景情况:
- 报告不足阻碍了对口腔健康研究的批判性评估.
- 需要在牙科研究的设计,进行,分析,解释和报告方面进行重大改进.
- 现有的报告准则需要对口腔健康研究进行整合和调整.
研究的目的:
- 引入OHStat指南,建立口腔健康研究的最低报告标准.
- 提高牙科观察研究和临床试验的透明度,完整性和可评估性.
- 通过整合和调整既定报告准则中的相关元素,提供统一的框架.
主要方法:
- 一个由统计学家和试验人员组成的特别工作组制定了OHStat指南.
- 从CONSORT,STROBE,CONSORT危害,SAMPL,CLIP和GRADE指南中进行了广泛的审查和整合原则.
- 将草稿发送给85家口腔健康期刊编辑,工作组成员和赞助商,随后与49名研究人员举行研讨会进行修订.
主要成果:
- "OHStat指南"为口腔健康研究报告提供了一个全面的框架.
- 指南强调临床上有意义的单位和置信区间,而不是P值.
- OHStat包括7条新指南,涉及抽象文本一致性,讨论结构和结论特异性.
结论:
- "OHStat指南"巩固和调整口腔健康研究的现有报告标准.
- 实施OHStat将提高牙科研究手稿中的信息质量和特异性.
- 这些指南旨在加强发表的口腔健康研究的批判性评估和整体质量.
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