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相关概念视频

Proteomics01:33

Proteomics

7.3K
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
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Genomics02:02

Genomics

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Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
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相关实验视频

Updated: Jun 21, 2025

High-throughput Gene Tagging in Trypanosoma brucei
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High-throughput Gene Tagging in Trypanosoma brucei

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三级动物基因组学和蛋白质组学

Gabriel Rinaldi1, Alex Loukas2, Javier Sotillo3

  • 1Department of Life Sciences, Aberystwyth University, Aberystwyth, UK.

Advances in experimental medicine and biology
|July 15, 2024
PubMed
概括
此摘要是机器生成的。

经常被忽视的热带疾病 - - 类动物感染 - - 在基因组学和蛋白质组学研究中取得了重大进展. 最近的进展突出了研究这些有影响力的寄生虫虫的新技术和资源.

关键词:
控制 控制 控制 控制 控制诊断 诊断 诊断 诊断 诊断基因组学就是基因组学.宿主与寄生者的关系致病性 致病性 致病性蛋白质组学是指蛋白质组学.治疗方法 治疗方法形虫感染的感染.迪格尼纳亚 (Digenea) 是一个

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Forward Genetics Screens Using Macrophages to Identify Toxoplasma gondii Genes Important for Resistance to IFN-&#947;-Dependent Cell Autonomous Immunity
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Forward Genetics Screens Using Macrophages to Identify Toxoplasma gondii Genes Important for Resistance to IFN-γ-Dependent Cell Autonomous Immunity

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QTL Mapping and CRISPR/Cas9 Editing to Identify a Drug Resistance Gene in Toxoplasma gondii
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QTL Mapping and CRISPR/Cas9 Editing to Identify a Drug Resistance Gene in Toxoplasma gondii

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QTL Mapping and CRISPR/Cas9 Editing to Identify a Drug Resistance Gene in Toxoplasma gondii
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科学领域:

  • 寄生虫学的寄生虫学
  • 热带医学 热带医学
  • 分子生物学分子生物学

背景情况:

  • 形动物感染在全球普遍存在,影响人类健康,农业和兽医.
  • 这些寄生虫影响着不同的宿主和组织,带来了重大的社会经济挑战.
  • 尽管它们很重要,但三动物生物学仍未得到充分研究.

研究的目的:

  • 审查近期三动物基因组学和蛋白质组学方面的进展.
  • 为了突出过去五年取得的进展.
  • 为分子研究引入新技术和资源.

主要方法:

  • 关于三动物基因组学和蛋白质组学的最新科学文献的综述.
  • 专注于过去五年内发表的研究.
  • 识别和讨论新兴技术和数据库.

主要成果:

  • 在将"omic"工具应用于三极研究方面取得了显著进展.
  • 基因组和蛋白质组数据越来越多地可用于各种三动物物种.
  • 新技术正在增强我们对三毛动物分子生物学的理解.

结论:

  • 最近的"omic"研究已经大大改善了我们对三叉生物学的理解.
  • 继续应用先进技术将进一步阐明三极管分子机制.
  • 可获得的资源对于未来对这些重要寄生虫的研究至关重要.