睡眠时间和高血压发病率之间的关联:对队列研究的系统审查和分析
Kaveh Hosseini1, Hamidreza Soleimani1, Kiarash Tavakoli1,2
1Tehran Heart Center, Cardiovascular Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
PloS one
|July 15, 2024
概括
短暂的睡眠时间会增加高血压的风险,尤其是在5小时以下. 女性更容易受到伤害. 长时间的睡眠时间没有增加高血压发病率的风险.
科学领域:
- 心脏病学 心脏病学
- 睡眠医学 睡眠医学
- 流行病学 流行病学
背景情况:
- 高血压 (HTN) 是一个重要的全球健康问题.
- 睡眠时间和HTN风险之间的关系受到争论.
- 不一致的证据需要对敏感人群进行进一步的调查.
研究的目的:
- 对睡眠时间和高血压发病风险进行元分析.
- 为了确定由于睡眠模式而面临更高风险的特定人群.
主要方法:
- 从2000年到2023年,对主要数据库 (PubMed,Embase,Scopus,Web of Science,ProQuest) 进行系统的文献搜索.
- 纳入对象研究,比较睡眠时间短/长,睡眠时间为7-8小时.
- 应用一个随机效应模型来组合风险比率 (RR) 和95%置信区间 (CI).
主要成果:
- 分析了16项涉及1,044,035名参与者的研究.
- 睡眠时间短 (<7-8小时) 显著增加了HTN风险 (HR:1.07,95%CI:1.06-1.09).
- 睡眠时间小于5小时 (HR:1.11) 和女性 (HR:1.07) 的风险更明显.
结论:
- 睡眠时间短暂是高血压发病的危险因素.
- 长时间的睡眠时间与HTN风险增加无关.
- 针对睡眠时间短的个体进行有针对性的干预对于预防HTN至关重要.
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