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Updated: Jun 21, 2025

Mutagenesis and Functional Selection Protocols for Directed Evolution of Proteins in E. coli
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Mutagenesis and Functional Selection Protocols for Directed Evolution of Proteins in E. coli

Published on: March 16, 2011

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集体过氧化物排毒决定了E. coli中的微生物突变率可塑性.

Rowan Green1, Hejie Wang2, Carol Botchey2

  • 1School of Natural Sciences, Faculty of Science & Engineering, University of Manchester, United Kingdom.

PLoS biology
|July 15, 2024
PubMed
概括

微生物突变率随着人口密度的增加而下降,这是由于过氧化的集体控制. 这种密度相关突变速率可塑性 (DAMP) 与过氧化物降解有关,突变速率作为一个动态特征.

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相关概念视频

Mismatch Repair01:20

Mismatch Repair

Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...
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