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Updated: Jun 21, 2025

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卡尔巴马西平口服给小鼠的胚胎-胎儿发育毒性

Subham Kumar Panda1, Naveen Kumar H M1, Pradeep Takawale1

  • 1Department of Developmental and Reproductive Toxicology, Vipragen Biosciences Private Limited, Mysuru, Karnataka, India.

Reproductive toxicology (Elmsford, N.Y.)
|July 15, 2024
PubMed
概括

卡巴马西平是一种抗药,显著影响了Wistar大鼠的产前发育. 即使在较低的剂量下,它也导致怀孕率下降和显著的胎儿形,包括大脑和骨异常.

关键词:
卡巴马西平是一种碳化合物.头骨面部 头骨面部 面部胚胎 - 胎儿 - 胚胎缺陷形态 缺陷形态是一个错误的形态.骨的骨架部分产性 产性 产性

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Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
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