在患有重度抑郁症或双相情感障碍的患者中,患病率和与疲劳相关的因素
Keming Gao1, Joseph R Calabrese1
1Mood Disorders Program, Department of Psychiatry, University Hospitals Cleveland Medical Center, Cleveland, OH, United States of America; Case Western Reserve University School of Medicine, Cleveland, OH, United States of America.
Journal of affective disorders
|July 15, 2024
概括
在患有重大抑郁症 (MDD) 和双相情感障碍 (BD) 的患者中,疲劳非常普遍. 抑郁症症状严重程度独立预测疲劳严重程度,强调需要综合治疗.
科学领域:
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
- 神经科学是一个神经科学.
背景情况:
- 疲劳是主要抑郁症 (MDD) 和双相情感障碍 (BD) 的常见和衰弱症状.
- 了解疲劳的患病率和相关因素对于这些情绪障碍的有效治疗策略至关重要.
研究的目的:
- 确定诊断为MDD或BD的患者疲劳的患病率.
- 在这个患者群体中调查与疲劳严重程度相关的临床因素.
主要方法:
- 一项涉及253名患有MDD或BD的门诊患者的横截面研究.
- 使用爱荷华疲劳量表 (IFS) 评估疲劳严重程度.
- 抑郁和焦虑症状使用快速抑郁症状清单 (QIDS-16-SR) 和自评测焦虑量表 (Zung-SAS) 进行了测量.
主要成果:
- 很大一部分患有MDD (41.2%) 和BD (45.0%) 的患者报告感到疲劳,其中许多患者感到严重疲劳.
- 用IFS测量的疲劳严重程度与用QIDS-16-SR.测量的抑郁严重程度有显著的相关性.
- 在控制共变量后,QIDS-16-SR得分仍然是MDD和BD患者疲劳严重程度的重要独立预测指标.
结论:
- 在患有MDD和BD的门诊患者中,疲劳非常普遍.
- 抑郁症症状严重程度与疲劳严重程度独立相关.
- 抑郁症状的完全消失对于管理MDD和BD疲劳很重要.
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