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Updated: Jun 21, 2025

Investigating the Alleviating Effects of Bacillus cereus Administration on Colitis through Gut Microbiota Modulation
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高卡纳比杰罗尔大麻提取物温和结肠炎和调节微生物组在炎症性肠病模型

Benjamin D Anderson1, Diana E Sepulveda1, Rahul Nachnani1

  • 1Departments of Biochemistry and Molecular Biology (B.D.A., A.B.) and Veterinary and Biomedical Sciences (J.J.K.), and One Health Microbiome Center, Huck Life Sciences Institute (J.E.B.), Pennsylvania State University, University Park, Pennsylvania; and Departments of Pharmacology (D.E.S., R.N., A.C.-R., M.D.C., W.M.R.-K.) and Anesthesiology & Perioperative Medicine (D.E.S.), Center for Cannabis & Natural Product Pharmaceutics (D.E.S., R.N., A.C.-R., M.D.C., J.E.B., J.J.K., W.M.R.-K.), and Divison of Gastroenterology & Hepatology, Department of Medicine (M.D.C., J.J.K.), Pennsylvania State University College of Medicine, Hershey, Pennsylvania.

The Journal of pharmacology and experimental therapeutics
|July 15, 2024
PubMed
概括

高大麻基醇 (CBG) 含量的大麻提取物在小鼠模型中显著降低了结肠炎的严重程度. 这种治疗改变了肠道微生物组,并使炎症代谢途径正常化,这表明了炎症性肠病 (IBD) 的潜在新疗法.

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