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治疗的堆型形:系统性审查和元分析的概述

Yang-Tao Chen¹, Zhao-Chu Wang¹, Ya-Meng Xie¹

¹Department of Anorectal Surgery, The Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou, 350004, China.

Asian journal of surgery

|July 15, 2024

概括

形形 (SH) 提供了诸如减少疼痛之类的好处,但会带来出血和复发的风险. 这份综述发现,现有的关于SH质量的系统性审查很低,敦促在解释研究结果时谨慎.

科学领域:

结肠直肠手术结肠直肠手术
基于证据的医学基于证据的医学.

背景情况:

套接式出血 (SH) 是一种常见的出血治疗方法.
现有的关于SH疗效的系统性审查 (SR) 和元分析 (MA) 已经得出了不一致的结论.
对于这些审查的质量仍然存在怀疑,需要全面的概述.

研究的目的:

评估现有的SRs/MAs在SH的疗效和并发症方面的质量.
为临床实践提供关于SH结果的可靠证据.
在删除重叠的随机对照试验 (RCT) 之后,对SH结果进行新的元分析.

主要方法:

在七个数据库中对SRs/MAs进行了全面的文献搜索,对SH疗效和并发症进行了全面的搜索,直到2023年10月.
包括的SRs/MAs使用AMSTAR-2,PRISMA 2020和GRADE评估工具进行了评估.
删除了重叠的RCT,并对提取的结果进行了新的元分析.

主要成果:

综述包括23个元分析,质量评估显示存在重大缺陷.
AMSTAR-2:11个质量极低,9个质量低,3个质量中等.
普利斯玛2020和GRADE评估也显示了报告和证据的质量问题.
新的元分析证实了SH在减轻术后疼痛方面的有效性 (OR=0.28,CI [0.15,0.55]),但强调了出血和失落复发的风险增加.

结论:

嵌合式形术是有效的减少术后疼痛,缩短手术时间,并改善伤口愈合.
然而,SH与手术后出血和失落复发的风险较高有关.
鉴于审查的元分析的质量较低,研究结果应谨慎解释.

关键词:

这种情况是出血.概述概述概述概述概述接质的形形症系统审查是系统的审查.

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