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Updated: Jun 21, 2025

Single-cell Analysis of Immunophenotype and Cytokine Production in Peripheral Whole Blood via Mass Cytometry
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单细胞转录组学分析公牛型类动物揭示了2型炎症性疾病中的免疫-风脉交叉

Tingting Liu1,2, Zhenzhen Wang1,2,3, Xiaotong Xue1,2

  • 1Hospital for Skin Diseases, Shandong First Medical University, Jinan, Shandong, China.

Nature communications
|July 15, 2024
PubMed
概括

这项研究揭示了免疫细胞和皮肤细胞在雄性皮虫 (BP) 中如何沟通. IL-13信号通路驱动这种交叉,增加血压患者的自身抗体和疾病严重程度.

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相关概念视频

T Cell Types and Functions01:24

T Cell Types and Functions

When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
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