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Updated: Jun 21, 2025

siRNA Screening to Identify Ubiquitin and Ubiquitin-like System Regulators of Biological Pathways in Cultured Mammalian Cells
10:43

siRNA Screening to Identify Ubiquitin and Ubiquitin-like System Regulators of Biological Pathways in Cultured Mammalian Cells

Published on: May 24, 2014

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脱化酶突变发生屏幕识别了一个USP43依赖的HIF-1转录反应

Tekle Pauzaite1, Niek Wit1, Rachel V Seear1

  • 1Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Jeffrey Cheah Biomedical Centre, Department of Medicine, University of Cambridge, Cambridge, CB2 0AW, United Kingdom.

The EMBO journal
|July 15, 2024
PubMed
概括

脱化酶 (DUBs) 调节氧气感应. 研究人员确定USP43对于通过增强HIF-1核积累而不是稳定性来激活低氧诱导因子 (HIF) 信号至关重要.

关键词:
在这里,dub,dub,dub,dub,dub,dub.消灭城市的消灭.在HIF中,我们可以看到HIF.氧气过低是因为缺氧.美国P43

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