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评估复发性性结肠炎患者的阳门功能
Qiaoyan Wu1,2, Tongyu Li3, Fenglian Deng1,2
1Department of Gastroenterology, The First Affiliated Hospital of Ningbo University, No. 59, Liuting Street, Zhejiang Province, Ningbo, 315010, China.
复发性性结肠炎 (UC) 患者表现出直肠敏感度升高和直肠功能受损,影响生活质量. 管理UC疾病活动,预防复发,解决焦虑是改善功能的关键.
科学领域:
- 胃肠病学 胃肠病学
- 结肠直肠手术 结肠直肠手术
- 炎症性肠道疾病研究研究
背景情况:
- 性结肠炎 (UC) 是一种原因不明的慢性炎症性肠病.
- 慢性UC可以导致远端结肠的功能永久性损伤.
- 直肠功能障碍是影响患者生活质量的重大并发症.
研究的目的:
- 在患有复发性UC的患者中调查直肠功能.
- 在复发性UC患者中确定影响直肠功能的因素.
主要方法:
- 对33名复发性UC患者和40名新诊断的UC患者进行前性研究 (2019年1月至2022年12月).
- 收集的临床数据,患者报告的得分,以及直肠功能评估.
- 采用回归分析来确定影响直肠功能的因素.
主要成果:
- 复发性UC患者显示CRP升高,便calprotectin,焦虑,抑郁和便失禁.
- 在复发性UC患者中,较低的BMI,血红蛋白,白蛋白和炎症性肠病问卷得分被注意到.
- 长时间的疾病持续时间和高便calprotectin水平独立地影响了初始感觉,排便量和急迫性值. 高焦虑分数也影响了排便量.
结论:
- 复发性UC与直肠敏感性增加和直肠功能受损有关.
- 这些功能缺陷显著损害了UC患者的生活质量.
- 积极的疾病管理,复发预防和减少焦虑对于改善直肠功能至关重要.
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