在接受治疗性血交换的患者中检查药物去除特征:一项追溯研究
Ugur Balaban1, Emre Kara1, Sherif Hanafy Mahmoud2
1Department of Clinical Pharmacy, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey.
概括
许多接受治疗性血交换 (TPE) 的患者接受潜在可移除的处方药. 这凸显了在TPE期间需要谨慎的药物管理,以确保有效的治疗.
科学领域:
- 药理学 药理学是指药理学的学科.
- 腎臟病學 (nephrology) 是一種醫學專業.
- 关键护理医学 关键护理医学
背景情况:
- 治疗性血交换 (TPE) 是一种从血液中去除有害物质的程序.
- 然而,TPE还可以无意中去除必要的药物,可能会影响治疗的疗效.
- 了解哪些药物被TPE去除对于患者的安全至关重要.
研究的目的:
- 为了确定可能通过TPE去除的处方药的频率.
- 为了分析接受TPE的患者的药物历史.
- 在TPE期间为临床实践提供有关药物管理的信息.
主要方法:
- 一个回顾性,单中心研究分析了244名患者的1087次TPE会话.
- 在TPE日内服用的处方药被审查.
- 药物根据其被TPE去除的可能性进行分类:"是" (可能会被移除),"可能" (可能会被移除),和"不" (不太可能被移除).
主要成果:
- 在3966份处方中,556份 (14.0%) 被分析为TPE可移除性.
- 21.8%可能会被移除 ("是"),36.5%可能会被移除 ("可能"),41.7%不太可能被移除 ("不").
- 显著的大多数患者 (83.6%) 接受至少一种可分析药物,83.8%的患者有潜在的可移除药物.
结论:
- 现实数据表明,在TPE患者中,很大一部分患者接受了可能通过该程序去除的药物.
- 这强调了在TPE期间谨慎选择药物和监测的重要性.
- 优化治疗结果需要仔细考虑药物-TPE相互作用.
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