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Updated: Jun 21, 2025

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PRRX1-OLR1轴支持CAFs介导的肺癌进展和免疫抑制

Yunhao Sun1, Kaijun Ying1, Jian Sun1

  • 1Department of Thoracic Surgery, The First People's Hospital of Yancheng City, The Yancheng Clinical College of Xuzhou Medical University, Yancheng, 224005, Jiangsu, People's Republic of China.

Cancer cell international
|July 15, 2024
PubMed
概括

与癌症相关的纤维细胞 (CAFs) 促进肺癌的生长和免疫逃避. 转录因子PRRX1通过增加OLR1表达来激活CAF,从而推动瘤的进展.

关键词:
这些CAF是CAF.免疫监视系统的监视肺癌是一种肺癌.一个OLR1一个OLR1这就是PRRX1的原因.

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