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关于制定和验证多药店评估分数的议定书
Jung Yin Tsang1,2,3, Matthew Sperrin4,5, Thomas Blakeman6,4
1Centre for Primary Care and Health Services Research, School of Health Sciences, University of Manchester, Manchester, M13 9PL, UK. jungyin.tsang@manchester.ac.uk.
一个新的多药房评估分数有助于识别潜在有问题的处方患者. 这一分数超出了简单的药物计数,以更好地分层风险的个人,以改善护理.
科学领域:
- 老年学是一门学科.
- 临床药房 临床药房
- 医疗保健服务研究 医疗服务研究
背景情况:
- 多药性,即每天使用多种药物,由于人口老龄化和多病症性,正在增加.
- 虽然有益,但多药可以导致不良药物事件,相互作用和糟糕的患者体验.
- 有问题的多药学涉及不适当的处方或未实现的治疗益处,需要细微的识别超出简单的药物计数.
研究的目的:
- 开发一个多药房评估分数 (PAS) 来识别异常处方水平的患者.
- 该PAS旨在标记潜在有问题的多药风险的个人.
主要方法:
- 使用药物计数,年龄,性别和长期条件构建了一个预测模型,以创建PAS.
- 通过将PAS与明确的 (STOPP/START) 和隐性 (药物适用性指数) 的处方措施进行比较来评估构造有效性.
- 预测有效性是通过回顾性队列研究来评估的,该研究检查了不同PAS水平的临床结果 (药物不良反应,住院,死亡率).
主要成果:
- 该研究成功构建了一个多药学评估分数.
- 验证分析探讨了构造和预测有效性,将得分与处方适当性和临床结果联系起来.
- 结果表明,PAS可以区分与多药学相关的风险水平.
结论:
- 一个全面的多药房评估分数提供了一种改进的方法来识别和风险分层的多药房患者.
- 这种方法超越了简单的药物计数和狭窄的标准,可以更好地确定护理的优先级.
- 该PAS有潜力增强多种药物患者的临床决策.
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