听力,平衡和死亡率:长度研究中的性别特异性模式
Jan E Berge1, Geir A Nilsen1, Frederik K Goplen1,2
1Department of Otorhinolaryngology, Head and Neck Surgery, Haukeland University Hospital, Bergen, Norway.
概括
听力损失与男性的死亡率增加有关,但与女性无关. 这项研究突出了听力与死于所有原因和心血管事件之间的关系的性别特异性.
科学领域:
- 听力学和耳鼻喉学
- 心血管健康 心血管健康
- 流行病学 流行病学
背景情况:
- 听力障碍是一个日益严重的公共卫生问题.
- 人们越来越多地认识到健康结果的性别差异.
- 听力损失,死亡率和心血管疾病之间的关系需要进一步调查.
研究的目的:
- 评估听力值与性别特定整体死亡率之间的关联.
- 评估听力值与急性心血管疾病死亡之间的联系.
- 确定姿势平衡是否调节这些关联.
主要方法:
- 进行了一项队列研究,涉及学术医院耳鼻喉科的1036名患者.
- 进行了听力测量和稳定测量,听力值是从纯色调平均值计算出来的.
- 在26年的随访期间,从挪威死亡原因登记处获得了死亡率数据.
主要成果:
- 听力值增加10dB与男性整体死亡率增加14%相关 (HR1.02-1.28,P=.02),但女性没有 (HR0.92-1.15,P=.60).
- 对于急性心血管死亡,听力值增加10dB显示男性的危险比率增加了57% (HR 1.21-2.05,P<.001),女性没有显著的关联 (P=.71).
- 调整姿势平衡并没有改变听力和死亡率之间的观察到的关联.
结论:
- 听力值与男性的整体死亡率和急性心血管死亡率有显著的关联.
- 在女性中,听力值和死亡率之间没有发现显著的关联.
- 这项研究强调了在听力学研究和临床实践中考虑性别差异的重要性.
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