癌症临床图书馆数据库 (CCLD) 来自韩国临床数据利用网络研究卓越 (K-CURE) 项目
Sangwon Lee1, Yeon Ho Choi1, Hak Min Kim1
1National Cancer Control Institute, National Cancer Center, Goyang, Korea.
Cancer research and treatment
|July 16, 2024
概括
癌症临床图书馆数据库 (CCLD) 为韩国癌症研究数据提供了一种标准化的方法. 这些数据库旨在通过克服以前常用数据模型的局限性来改进多中心癌症研究.
科学领域:
- 在瘤学瘤学.
- 生物医学信息学 生物医学信息学
- 数据科学数据科学数据科学
背景情况:
- 常用数据模型 (CDM) 在医疗保健中广泛使用,但在癌症研究中应用有限.
- 需要标准化癌症特定数据库,以促进强大的多中心癌症研究.
研究的目的:
- 描述韩国癌症临床图书馆数据库 (CCLD) 的开发和实施情况.
- 建立一个标准化的癌症数据资源,用于韩国-临床数据利用网络研究卓越 (K-CURE) 项目的研究.
主要方法:
- 15家医院和14个学术协会正在为10种癌症类型建立CCLD.
- 专家定义和标准化关键的临床数据项目,创建一个统一的模式.
- 每年通过六西格玛质量控制收集全面的患者数据 (诊断,治疗,结果).
主要成果:
- 韩国主要机构正在为10种主要癌症类型开发CCLD.
- 数据安全通过假名化和封闭的分析环境来确保.
- 一个K-CURE门户便于研究人员访问,等待IRB和数据审查委员会批准.
结论:
- 在韩国,CCLDs是一个开创性的,标准化的癌症特定数据库.
- 预计这一举措将克服现有CDM的局限性.
- CCLDs将为韩国的多中心癌症研究提供一个宝贵的资源.
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