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患有急性单侧静脉病变的患者的thalamus功能连接性发生变化:休息状态fMRI研究

Zhengwei Chen¹, Yaxian Cai², Yueji Liu¹

¹Department of Neurology, Second Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China.

Frontiers in neuroscience

|July 16, 2024

概括

急性单侧带病 (AUVP) 涉及改变了丘脑的功能连接. 这项研究揭示了状体 - 垂体通路的减少和状体 - 感官 / 视觉通路的增加,有助于理解AUVP患者的中央补偿机制.

科学领域:

神经科学是一个神经科学.
医疗成像医学成像
静脉管系统疾病静脉管系统疾病

背景情况:

急性单侧带病 (AUVP) 是外周的常见原因.
中央前庭补偿对于AUVP恢复至关重要.
在AUVP的补偿机制中,丘脑的作用还没有得到充分的研究.

研究的目的:

在AUVP患者中调查丘脑静止状态功能连接 (FC) 的变化.
探索改变的胸膜FC与AUVP中的临床特征之间的关系.

主要方法:

功能磁共振成像 (fMRI) 和3D-T1数据来自40名AUVP患者和35名健康对照 (HC).
基于双边 thalamus 功能连接 (FC) 的种子分析.
皮尔森的部分相关性,以评估FC和临床数据之间的关联.

主要成果:

与HC相比,AUVP患者表现出thalamus和insula/supramarginal gyrus之间的FC降低.
在AUVP患者中,观察到甲状腺和后中心,中额和中尾之间增加了FC.
在AUVP患者中,thalamo-insular FC与道值负相关.

结论:

这项研究提供了AUVP中被改变的甲状腺皮层路径的初步证据.
研究结果表明,状体 - 垂体路径的减少和状体 - 垂体体体感觉/视觉路径的增加有助于中央补偿.
了解这些胸膜变化可以更好地了解AUVP的潜在补偿机制.

关键词:

急性单侧前庭病变急性单侧前庭病变功能连接性的功能连接性静止状态的fMRI进行.泰拉姆斯 (thalamus) 是一个神经系统.在前庭补偿方面,前庭补偿.在前置神经炎中,前置神经炎

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