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免疫性亡期间CX3CL1的释放与增强的抗瘤免疫力有关

Faye Naessens1,2, Robin Demuynck1,2, Olga Vershinina3

  • 1Cell Death Investigation and Therapy Laboratory, Anatomy and Embryology Unit, Department of Human Structure and Repair, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.

Frontiers in immunology
|July 16, 2024
PubMed
概括

化学物质CX3CL1 (fractalkine) 从垂死的癌细胞中释放出来,增强了免疫细胞死亡 (ICD). 这项研究表明CX3CL1促进了自适应性免疫反应,改善了黑色素瘤模型中的生存率,并与患者的更好的结果相关联.

关键词:
在CX3CL1中.化学物质 (chemokines) 是一种化学物质.细胞因子 细胞因子弗拉克塔尔基因 (Fractalkine) 是一种蛋白质.免疫原性亡 (apoptosis) 是一种免疫性亡.免疫性细胞死亡 免疫性细胞死亡

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