作为抗抗微生物和抗病毒耐药性的天然来源,Pistacia vera L
Giuseppina Mandalari1, Rosamaria Pennisi1, Teresa Gervasi2
1Department of Chemical, Biological, Pharmaceutical, and Environmental Science, University of Messina, Messina, Italy.
Frontiers in microbiology
|July 16, 2024
概括
pistachio 的植物化学物质显示出对抗抗微生物和抗病毒耐药性的承诺. 研究表明,对于黄金葡萄球菌 (Staphylococcus aureus) 皮肤和眼部疹感染的潜在局部治疗方法.
科学领域:
- 营养科学 营养科学
- 药理学 药理学是指药理学的学科.
- 微生物学 微生物学
背景情况:
- 全球抗微生物和抗病毒耐药性增加需要新的治疗策略.
- 核桃富含多种植物化学物质,包括胡卜素,酸,黄酸和酸盐.
- 这些尾果衍生化合物表现出固有的抗微生物和抗病毒特性.
研究的目的:
- 审查花生果及其成分的抗菌和抗病毒潜力.
- 探索 pistachio 化合物作为独立剂和组合疗法的疗效.
- 为了确定 pistachio-derived治疗药物的潜在应用.
主要方法:
- 对调查 pistachio坚果提取物和化合物的研究的文献综述.
- 对抗细菌菌株抗微生物活性的体外数据的分析.
- 对特定病毒的抗病毒活性评估,包括简单疹病毒1 (HSV-1).
主要成果:
- pistachio 提取物显示出显著的抗菌活性,特别是在对抗像金黄色葡萄球菌 (Staphylococcus aureus) 这样的阳性细菌.
- 针对简单疹病毒1 (HSV-1) 观察到抗病毒作用.
- 发现在 pistachio 中的一种化合物 zeaxanthin 能够抑制 HSV-1 细胞的附着,透和病毒 DNA 的合成.
结论:
- 核桃植物化学物质具有显著的抗微生物和抗病毒潜力.
- pistachio 提取物和衍生品在局部治疗金黄色葡萄球菌 (Staphylococcus aureus) 皮肤感染方面显示出前途.
- 有潜在的应用存在于治疗眼部疹感染与 pistachio-derived化合物.
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